“Europe is missing too many innovations.”

I had the pleasure of welcoming Pierre-Henri Belin, the Co-Founder and CEO of Xcube.Bio — an innovative company that accelerates biopharma market entry across Europe.

By combining capital, deep expertise, and industry knowledge, Xcube.Bio helps mitigate risks and launch transformative solutions.

Pierre-Henri is a leading voice in pharmaceutical innovation and healthcare transformation. In this episode, he shares a bold vision to bridge one of Europe’s most urgent healthcare gaps: the slow access to new drugs for European patients.

In this conversation, we discuss:
◾️ The alarming gap between the United States and Europe — with more than 100 new drugs available in the US but still not accessible to European patients.
◾️ Why this gap exists, from fragmented regulatory systems to national-level decision-making and the lack of early collaboration between key actors.
◾️ The consequences for patients, innovation, and the competitiveness of Europe’s healthcare ecosystem.
◾️ Pierre-Henri’s proposed model, built on transparency, collaboration, and shared responsibility — connecting innovators, regulators, and patients earlier in the process.
◾️ A message of hope, showing that Europe can reinvent its system without sacrificing safety or trust, but only if we act collectively and decisively.

A clear, concrete, and inspiring episode that sheds light on how Europe can regain its leadership in healthcare innovation.

👉 This is one of those conversations that stays with you long after you listen. Enjoy the episode!

Many thanks to Xcube.Bio for supporting this episode. Their partnership allows us to push our explorations further — but the spirit of Pharma Minds remains unchanged: full editorial independence and complete freedom in choosing our guests.

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Chapters:
00:00 – Introduction
01:51 – Why US strategies don’t work in Europe
07:23 – How Xcube.bio reinvented market entry for biotech
11:00 – A new win-win model that shares risks and rewards
13:03 – 100 biotech conversations: what ceos really struggle with
15:38 – How Xcube.bio helps late-stage biotech reach patients faster
18:08 – What European payers expect — and why value matters most
21:44 – US vs Europe: two very different market realities
30:44 – Who takes the risk when a launch fails
33:44 – Launching in Europe: It's not only a matter of money
39:17 – Why Chinese biotechs and global players look to Europe
45:33 – The future of biotech in Europe — threats and opportunities
51:38 – The projets of Xcube.bio for the next 5 years
53:31 – Pierre-Henri's advice for European policymakers

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Find Pierre-Henri Belin:
LinkedIn: https://www.linkedin.com/in/phbelin/?originalSubdomain=ch
Xcube.Bio: https://xcube.bio/

Resources mentioned in the episode:
📌 Deloitte Partner: Hanno Ronte
📌 M&A Specialist: Jan Boehler
📌 Former CFO of Big Pharma: Ludo Ooms
📌 Bluebird Bio (now Genetix Biotherapeutics): https://share.google/KHHhGp5HPvr5sDNkE
📌 Agios: www.agios.com

Pharma Minds episodes mentioned:
📌 Frédéric Prince on the Bluebird adventure in France (in English): https://youtu.be/BLrJ5viHyvM?si=7QxKSBSC-IvUNtAM

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